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Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport
This study was aimed to investigate the effect of human PON1 overexpression in mice on cholesterol efflux and reverse cholesterol transport. PON1 overexpression in PON1-Tg mice induced a significant 3-fold (p<0.0001) increase in plasma paraoxonase activity and a significant ~30% (p<0.0001) inc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344486/ https://www.ncbi.nlm.nih.gov/pubmed/28278274 http://dx.doi.org/10.1371/journal.pone.0173385 |