Cargando…

Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport

This study was aimed to investigate the effect of human PON1 overexpression in mice on cholesterol efflux and reverse cholesterol transport. PON1 overexpression in PON1-Tg mice induced a significant 3-fold (p<0.0001) increase in plasma paraoxonase activity and a significant ~30% (p<0.0001) inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikhlef, Souade, Berrougui, Hicham, Kamtchueng Simo, Olivier, Zerif, Echarki, Khalil, Abdelouahed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344486/
https://www.ncbi.nlm.nih.gov/pubmed/28278274
http://dx.doi.org/10.1371/journal.pone.0173385