Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods

Short single-stranded oligonucleotides represent a class of promising therapeutics with diverse application areas. Antisense oligonucleotides, for example, can interfere with various processes involved in mRNA processing through complementary base pairing. Also RNA interference can be regulated by a...

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Detalles Bibliográficos
Autores principales: Heissig, Philipp, Schrimpf, Waldemar, Hadwiger, Philipp, Wagner, Ernst, Lamb, Don C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344492/
https://www.ncbi.nlm.nih.gov/pubmed/28278199
http://dx.doi.org/10.1371/journal.pone.0173401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344492/
https://www.ncbi.nlm.nih.gov/pubmed/28278199
http://dx.doi.org/10.1371/journal.pone.0173401

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