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OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans

Ethnic groups can display differential genetic susceptibility to infectious diseases. The arthropod-born viral dengue disease is one such disease, with empirical and limited genetic evidence showing that African ancestry may be protective against the haemorrhagic phenotype. Global ancestry analysis...

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Detalles Bibliográficos
Autores principales: Sierra, Beatriz, Triska, Petr, Soares, Pedro, Garcia, Gissel, Perez, Ana B., Aguirre, Eglys, Oliveira, Marisa, Cavadas, Bruno, Regnault, Béatrice, Alvarez, Mayling, Ruiz, Didye, Samuels, David C., Sakuntabhai, Anavaj, Pereira, Luisa, Guzman, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344536/
https://www.ncbi.nlm.nih.gov/pubmed/28241052
http://dx.doi.org/10.1371/journal.ppat.1006220