Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

Understanding the mechanism of resistance of genes to reactivation will help improve the success of nuclear reprogramming. Using mouse embryonic fibroblast nuclei with normal or reduced DNA methylation in combination with chromatin modifiers able to erase H3K9me3, H3K27me3, and H2AK119ub1 from trans...

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Detalles Bibliográficos
Autores principales: Jullien, Jerome, Vodnala, Munender, Pasque, Vincent, Oikawa, Mami, Miyamoto, Kei, Allen, George, David, Sarah Anne, Brochard, Vincent, Wang, Stan, Bradshaw, Charles, Koseki, Haruhiko, Sartorelli, Vittorio, Beaujean, Nathalie, Gurdon, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344684/
https://www.ncbi.nlm.nih.gov/pubmed/28257702
http://dx.doi.org/10.1016/j.molcel.2017.01.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344684/
https://www.ncbi.nlm.nih.gov/pubmed/28257702
http://dx.doi.org/10.1016/j.molcel.2017.01.030

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