Cyclooxygenase-2 Inhibition Limits Angiotensin II-Induced DNA Oxidation and Protein Nitration in Humans

Compared to other cyclooxygenase-2 inhibitors, celecoxib is associated with a lower cardiovascular risk, though the mechanism remains unclear. Angiotensin II is an important mediator of oxidative stress in the pathophysiology of vascular disease. Cyclooxygenase-2 may modify the effects of angiotensi...

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Detalles Bibliográficos
Autores principales: Pialoux, Vincent, Poulin, Marc J., Hemmelgarn, Brenda R., Muruve, Daniel A., Chirico, Erica N., Faes, Camille, Sola, Darlene Y., Ahmed, Sofia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344903/
https://www.ncbi.nlm.nih.gov/pubmed/28344559
http://dx.doi.org/10.3389/fphys.2017.00138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344903/
https://www.ncbi.nlm.nih.gov/pubmed/28344559
http://dx.doi.org/10.3389/fphys.2017.00138

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