Prevalence of NRAS, PTEN and AKT1 gene mutations in the central nervous system metastases of non-small cell lung cancer

Somatic mutations in NRAS, PTEN and AKT1 genes are rarely (~1%) reported in primary NSCLC, but their role in carcinogenesis have been proven. Therefore, we assessed the frequency of them in 145 FFPE tissue samples from CNS metastases of NSCLC using the real-time PCR technique. We identified four (tw...

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Detalles Bibliográficos
Autores principales: Nicoś, Marcin, Krawczyk, Paweł, Jarosz, Bożena, Sawicki, Marek, Trojanowski, Tomasz, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344951/
https://www.ncbi.nlm.nih.gov/pubmed/28097440
http://dx.doi.org/10.1007/s10014-016-0276-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344951/
https://www.ncbi.nlm.nih.gov/pubmed/28097440
http://dx.doi.org/10.1007/s10014-016-0276-2

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