PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

Poly(ADP-ribosyl)ation (PARylation) is mainly catalysed by poly-ADP-ribose polymerase 1 (PARP1), whose role in gene transcription modulation has been well established. Here we show that, in response to LPS exposure, PARP1 interacts with the adenylateuridylate-rich element-binding protein embryonic l...

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Detalles Bibliográficos
Autores principales: Ke, Yueshuang, Han, Yanlong, Guo, Xiaolan, Wen, Jitao, Wang, Ke, Jiang, Xue, Tian, Xue, Ba, Xueqing, Boldogh, Istvan, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344980/
https://www.ncbi.nlm.nih.gov/pubmed/28272405
http://dx.doi.org/10.1038/ncomms14632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344980/
https://www.ncbi.nlm.nih.gov/pubmed/28272405
http://dx.doi.org/10.1038/ncomms14632

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