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Reactive oxygen species are required for zoledronic acid-induced apoptosis in osteoclast precursors and mature osteoclast-like cells

Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important strategy to treat osteoclast-related diseases, such as osteoporosis, inflammatory bone loss, and malignant bone metastasis. However, the mechanism by which apoptosis is induced in the osteoclasts and their pre...

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Detalles Bibliográficos
Autores principales: Tai, Ta-Wei, Chen, Ching-Yu, Su, Fong-Chin, Tu, Yuan-Kun, Tsai, Tsung-Ting, Lin, Chiou-Feng, Jou, I.-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345019/
https://www.ncbi.nlm.nih.gov/pubmed/28281643
http://dx.doi.org/10.1038/srep44245