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Reactive oxygen species are required for zoledronic acid-induced apoptosis in osteoclast precursors and mature osteoclast-like cells
Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important strategy to treat osteoclast-related diseases, such as osteoporosis, inflammatory bone loss, and malignant bone metastasis. However, the mechanism by which apoptosis is induced in the osteoclasts and their pre...
Autores principales: | Tai, Ta-Wei, Chen, Ching-Yu, Su, Fong-Chin, Tu, Yuan-Kun, Tsai, Tsung-Ting, Lin, Chiou-Feng, Jou, I.-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345019/ https://www.ncbi.nlm.nih.gov/pubmed/28281643 http://dx.doi.org/10.1038/srep44245 |
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