Identification of the Beer Component Hordenine as Food-Derived Dopamine D2 Receptor Agonist by Virtual Screening a 3D Compound Database

The dopamine D2 receptor (D2R) is involved in food reward and compulsive food intake. The present study developed a virtual screening (VS) method to identify food components, which may modulate D2R signalling. In contrast to their common applications in drug discovery, VS methods are rarely applied...

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Detalles Bibliográficos
Autores principales: Sommer, Thomas, Hübner, Harald, El Kerdawy, Ahmed, Gmeiner, Peter, Pischetsrieder, Monika, Clark, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345022/
https://www.ncbi.nlm.nih.gov/pubmed/28281694
http://dx.doi.org/10.1038/srep44201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345022/
https://www.ncbi.nlm.nih.gov/pubmed/28281694
http://dx.doi.org/10.1038/srep44201

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