Potent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy

A large number of human diseases are caused by chronic tissue injury with fibrosis potentially leading to organ failure. There is a need for more effective anti-fibrotic therapies. Congenital muscular dystrophy type 1A (MDC1A) is a devastating form of muscular dystrophy caused by laminin α2 chain-de...

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Detalles Bibliográficos
Autores principales: Gawlik, Kinga I., Holmberg, Johan, Svensson, Martina, Einerborg, Mikaela, Oliveira, Bernardo M. S., Deierborg, Tomas, Durbeej, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345027/
https://www.ncbi.nlm.nih.gov/pubmed/28281577
http://dx.doi.org/10.1038/srep44059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345027/
https://www.ncbi.nlm.nih.gov/pubmed/28281577
http://dx.doi.org/10.1038/srep44059

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