Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice

We previously demonstrated that polymorphisms in the carnosinase-1 gene (CNDP1) determine the risk of nephropathy in type 2 diabetic patients. Carnosine, the substrate of the enzyme encoded by this gene, is considered renoprotective and could possibly be used to treat diabetic nephropathy (DN). In t...

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Detalles Bibliográficos
Autores principales: Albrecht, Thomas, Schilperoort, Maaike, Zhang, Shiqi, Braun, Jana D., Qiu, Jiedong, Rodriguez, Angelica, Pastene, Diego O., Krämer, Bernhard K., Köppel, Hannes, Baelde, Hans, de Heer, Emile, Anna Altomare, Alessandra, Regazzoni, Luca, Denisi, Alessandra, Aldini, Giancarlo, van den Born, Jacob, Yard, Benito A., Hauske, Sibylle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345040/
https://www.ncbi.nlm.nih.gov/pubmed/28281693
http://dx.doi.org/10.1038/srep44492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345040/
https://www.ncbi.nlm.nih.gov/pubmed/28281693
http://dx.doi.org/10.1038/srep44492

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