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New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Cationic amphiphilic drugs (CADs) comprise a wide variety of different substance classes such as antidepressants, antipsychotics, and antiarrhythmics. It is well recognized that CADs accumulate in certain intracellular compartments leading to specific morphological changes of cells. So far, no adequ...

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Detalles Bibliográficos
Autores principales: Vater, Magdalena, Möckl, Leonhard, Gormanns, Vanessa, Schultz Fademrecht, Carsten, Mallmann, Anna M., Ziegart-Sadowska, Karolina, Zaba, Monika, Frevert, Marie L., Bräuchle, Christoph, Holsboer, Florian, Rein, Theo, Schmidt, Ulrike, Kirmeier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345070/
https://www.ncbi.nlm.nih.gov/pubmed/28281674
http://dx.doi.org/10.1038/srep44277