Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease

Therapeutic targets are needed to develop neuroprotective treatments for Parkinson’s disease (PD). Mitophagy, the selective autophagic elimination of dysfunctional mitochondria, is essential for the maintenance of mitochondrial integrity and is predominantly regulated by the PINK1/Parkin-mediated pa...

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Detalles Bibliográficos
Autores principales: Koentjoro, Brianada, Park, Jin-Sung, Sue, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345073/
https://www.ncbi.nlm.nih.gov/pubmed/28281653
http://dx.doi.org/10.1038/srep44373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345073/
https://www.ncbi.nlm.nih.gov/pubmed/28281653
http://dx.doi.org/10.1038/srep44373

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