Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency

Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The...

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Detalles Bibliográficos
Autores principales: Fleury Curado, Thomaz, Fishbein, Kenneth, Pho, Huy, Brennick, Michael, Dergacheva, Olga, Sennes, Luiz U., Pham, Luu V., Ladenheim, Ellen E., Spencer, Richard, Mendelowitz, David, Schwartz, Alan R., Polotsky, Vsevolod Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345079/
https://www.ncbi.nlm.nih.gov/pubmed/28281681
http://dx.doi.org/10.1038/srep44392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345079/
https://www.ncbi.nlm.nih.gov/pubmed/28281681
http://dx.doi.org/10.1038/srep44392

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