Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes

The Target of Rapamycin (TOR) signalling network plays important roles in aging and disease. The AMP-activated protein kinase (AMPK) and the Gsk3 kinase inhibit TOR during stress. We performed genetic interaction screens using synthetic genetic arrays (SGA) with gsk3 and amk2 as query mutants, the l...

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Detalles Bibliográficos
Autores principales: Rallis, Charalampos, Townsend, StJohn, Bähler, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345095/
https://www.ncbi.nlm.nih.gov/pubmed/28281664
http://dx.doi.org/10.1038/srep44257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345095/
https://www.ncbi.nlm.nih.gov/pubmed/28281664
http://dx.doi.org/10.1038/srep44257

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