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PPIP5K1 Suppresses Etoposide-triggered Apoptosis

Inositol hexakisphosphate kinase 2 (IP6K2) potentiates pro-apoptotic signalling and increases the sensitivity of mammalian cells to cytotoxic agents. Diphosphoinositol pentakisphosphate kinase (PPIP5K) generates inositol pyrophosphates (InsPPs) that are structurally distinct from those produced by I...

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Detalles Bibliográficos
Autores principales: Machkalyan, Gayane, Hèbert, Terence E., Miller, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345130/
https://www.ncbi.nlm.nih.gov/pubmed/31051014
http://dx.doi.org/10.5334/1750-2187-11-4