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LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer

BACKGROUND: Conventional tubular adenomas are frequently detected in patients undergoing average risk screening colonoscopy and are over-represented in patients who will develop colorectal cancer (CRC). Whether features of adenomas could serve as predictors of synchronous CRC is not known. Here, we...

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Detalles Bibliográficos
Autores principales: Jiang, Alice Chu, Buckingham, Lela, Barbanera, William, Korang, Amoah Yeboah, Bishesari, Faraz, Melson, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345219/
https://www.ncbi.nlm.nih.gov/pubmed/28293326
http://dx.doi.org/10.1186/s13148-017-0325-7