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Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common joint disease worldwide. In the past decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA. A potential mechanism of MSC-based therapies has been attributed to the paracrine secretion of trophic factors, in which exosom...

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Detalles Bibliográficos
Autores principales: Zhu, Yu, Wang, Yuchen, Zhao, Bizeng, Niu, Xin, Hu, Bin, Li, Qing, Zhang, Juntao, Ding, Jian, Chen, Yunfeng, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345222/
https://www.ncbi.nlm.nih.gov/pubmed/28279188
http://dx.doi.org/10.1186/s13287-017-0510-9