rs35301225 polymorphism in miR-34a promotes development of human colon cancer by deregulation of 3′UTR in E2F1 in Chinese population

BACKGROUND: Previous reports have revealed that down-regulation of miR-34a expression can promote colorectal cancer (CRC) cell growth by targeting cell cycle-related transcriptional factor E2F1. To date, the function of the single nucleotide polymorphism (SNP) located in the mature region of miR-34a...

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Detalles Bibliográficos
Autores principales: Jiang, Haiqiang, Ge, Fengyuan, Hu, Beina, Wu, Lamei, Yang, Huijian, Wang, Huiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345262/
https://www.ncbi.nlm.nih.gov/pubmed/28293146
http://dx.doi.org/10.1186/s12935-017-0402-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345262/
https://www.ncbi.nlm.nih.gov/pubmed/28293146
http://dx.doi.org/10.1186/s12935-017-0402-1

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