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rs35301225 polymorphism in miR-34a promotes development of human colon cancer by deregulation of 3′UTR in E2F1 in Chinese population

BACKGROUND: Previous reports have revealed that down-regulation of miR-34a expression can promote colorectal cancer (CRC) cell growth by targeting cell cycle-related transcriptional factor E2F1. To date, the function of the single nucleotide polymorphism (SNP) located in the mature region of miR-34a...

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Detalles Bibliográficos
Autores principales:	Jiang, Haiqiang, Ge, Fengyuan, Hu, Beina, Wu, Lamei, Yang, Huijian, Wang, Huiyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345262/ https://www.ncbi.nlm.nih.gov/pubmed/28293146 http://dx.doi.org/10.1186/s12935-017-0402-1

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