Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia

BACKGROUND: Improved diagnostics for typhoid are needed; a typhoid controlled human infection model may accelerate their development and translation. Here, we evaluated a blood culture-PCR assay for detecting infection after controlled human infection with S. Typhi and compared test performance with...

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Detalles Bibliográficos
Autores principales: Darton, Thomas C., Zhou, Liqing, Blohmke, Christoph J., Jones, Claire, Waddington, Claire S., Baker, Stephen, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345565/
https://www.ncbi.nlm.nih.gov/pubmed/28130144
http://dx.doi.org/10.1016/j.jinf.2017.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345565/
https://www.ncbi.nlm.nih.gov/pubmed/28130144
http://dx.doi.org/10.1016/j.jinf.2017.01.006

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