Cargando…
Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia
BACKGROUND: Improved diagnostics for typhoid are needed; a typhoid controlled human infection model may accelerate their development and translation. Here, we evaluated a blood culture-PCR assay for detecting infection after controlled human infection with S. Typhi and compared test performance with...
Autores principales: | Darton, Thomas C., Zhou, Liqing, Blohmke, Christoph J., Jones, Claire, Waddington, Claire S., Baker, Stephen, Pollard, Andrew J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345565/ https://www.ncbi.nlm.nih.gov/pubmed/28130144 http://dx.doi.org/10.1016/j.jinf.2017.01.006 |
Ejemplares similares
-
Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever
por: Salerno-Gonçalves, Rosângela, et al.
Publicado: (2022) -
Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model
por: Fresnay, Stephanie, et al.
Publicado: (2017) -
Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans
por: Fresnay, Stephanie, et al.
Publicado: (2016) -
Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans
por: Darton, Thomas C., et al.
Publicado: (2015) -
Development and Evaluation of a Blood Culture PCR Assay for Rapid Detection of Salmonella Paratyphi A in Clinical Samples
por: Zhou, Liqing, et al.
Publicado: (2016)