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Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet’s disease severity

Behçet’s disease (BD) activity is characterised by sustained, over-exuberant immune activation, yet the underlying mechanisms leading to active BD state are poorly defined. Herein, we show that the human cathelicidin derived antimicrobial peptide LL37 associates with and directs plasma extracellular...

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Detalles Bibliográficos
Autores principales: Kahraman, Tamer, Gucluler, Gozde, Simsek, Ismail, Yagci, Fuat Cem, Yildirim, Muzaffer, Ozen, Can, Dinc, Ayhan, Gursel, Mayda, Ikromzoda, Lolai, Sutlu, Tolga, Gay, Stephen, Gursel, Ihsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345581/
https://www.ncbi.nlm.nih.gov/pubmed/28326169
http://dx.doi.org/10.1080/20013078.2017.1284449