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Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet’s disease severity
Behçet’s disease (BD) activity is characterised by sustained, over-exuberant immune activation, yet the underlying mechanisms leading to active BD state are poorly defined. Herein, we show that the human cathelicidin derived antimicrobial peptide LL37 associates with and directs plasma extracellular...
Autores principales: | Kahraman, Tamer, Gucluler, Gozde, Simsek, Ismail, Yagci, Fuat Cem, Yildirim, Muzaffer, Ozen, Can, Dinc, Ayhan, Gursel, Mayda, Ikromzoda, Lolai, Sutlu, Tolga, Gay, Stephen, Gursel, Ihsan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345581/ https://www.ncbi.nlm.nih.gov/pubmed/28326169 http://dx.doi.org/10.1080/20013078.2017.1284449 |
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