SHH Protein Variance in the Limb Bud Is Constrained by Feedback Regulation and Correlates with Altered Digit Patterning

mRNA variance has been proposed to play key roles in normal development, population fitness, adaptability, and disease. While variance in gene expression levels may be beneficial for certain cellular processes, for example in a cell’s ability to respond to external stimuli, variance may be detriment...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Rui, Lee, Chanmi, Lawson, Lisa Y., Svete, Lillian J., McIntyre, Lauren M., Harfe, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345715/
https://www.ncbi.nlm.nih.gov/pubmed/28131983
http://dx.doi.org/10.1534/g3.116.033019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345715/
https://www.ncbi.nlm.nih.gov/pubmed/28131983
http://dx.doi.org/10.1534/g3.116.033019

Ejemplares similares