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The essential and downstream common proteins of amyotrophic lateral sclerosis: A protein-protein interaction network analysis

Amyotrophic Lateral Sclerosis (ALS) is a devastative neurodegenerative disease characterized by selective loss of motoneurons. While several breakthroughs have been made in identifying ALS genetic defects, the detailed molecular mechanisms are still unclear. These genetic defects involve in numerous...

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Detalles Bibliográficos
Autores principales: Mao, Yimin, Kuo, Su-Wei, Chen, Le, Heckman, C. J., Jiang, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345759/
https://www.ncbi.nlm.nih.gov/pubmed/28282387
http://dx.doi.org/10.1371/journal.pone.0172246