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Tor1 and CK2 kinases control a switch between alternative ribosome biogenesis pathways in a growth-dependent manner

Ribosome biogenesis is a major energy-consuming process in the cell that has to be rapidly down-regulated in response to stress or nutrient depletion. The target of rapamycin 1 (Tor1) pathway regulates synthesis of ribosomal RNA (rRNA) at the level of transcription initiation. It remains unclear whe...

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Detalles Bibliográficos
Autores principales: Kos-Braun, Isabelle C., Jung, Ilona, Koš, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345768/
https://www.ncbi.nlm.nih.gov/pubmed/28282370
http://dx.doi.org/10.1371/journal.pbio.2000245