Interactions within the MHC contribute to the genetic architecture of celiac disease

Interaction analysis of GWAS can detect signal that would be ignored by single variant analysis, yet few robust interactions in humans have been detected. Recent work has highlighted interactions in the MHC region between known HLA risk haplotypes for various autoimmune diseases. To better understan...

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Detalles Bibliográficos
Autores principales: Goudey, Benjamin, Abraham, Gad, Kikianty, Eder, Wang, Qiao, Rawlinson, Dave, Shi, Fan, Haviv, Izhak, Stern, Linda, Kowalczyk, Adam, Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345796/
https://www.ncbi.nlm.nih.gov/pubmed/28282431
http://dx.doi.org/10.1371/journal.pone.0172826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345796/
https://www.ncbi.nlm.nih.gov/pubmed/28282431
http://dx.doi.org/10.1371/journal.pone.0172826

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