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Regions of very low H3K27me3 partition the Drosophila genome into topological domains

It is now well established that eukaryote genomes have a common architectural organization into topologically associated domains (TADs) and evidence is accumulating that this organization plays an important role in gene regulation. However, the mechanisms that partition the genome into TADs and the...

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Detalles Bibliográficos
Autores principales: El-Sharnouby, Sherif, Fischer, Bettina, Magbanua, Jose Paolo, Umans, Benjamin, Flower, Rosalyn, Choo, Siew Woh, Russell, Steven, White, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345799/
https://www.ncbi.nlm.nih.gov/pubmed/28282436
http://dx.doi.org/10.1371/journal.pone.0172725