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A new Caenorhabditis elegans model of human huntingtin 513 aggregation and toxicity in body wall muscles
Expanded polyglutamine repeats in different proteins are the known determinants of at least nine progressive neurodegenerative disorders whose symptoms include cognitive and motor impairment that worsen as patients age. One such disorder is Huntington’s Disease (HD) that is caused by a polyglutamine...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345860/ https://www.ncbi.nlm.nih.gov/pubmed/28282438 http://dx.doi.org/10.1371/journal.pone.0173644 |