Cargando…

Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery

BACKGROUND: We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn. Although TXA is commonly used to reduce perioperative blood loss during various surgeries, its potential to induce intraoperat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohashi, Nobuko, Ohashi, Masayuki, Endo, Naoto, Kohno, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345863/
https://www.ncbi.nlm.nih.gov/pubmed/28282425
http://dx.doi.org/10.1371/journal.pone.0173622