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Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects

Several drugs have recently been reported to induce rapid antidepressant effects in clinical trials and rodent models. Although the cellular mechanisms involved remain unclear, reports suggest that increased glutamate transmission contributes to these effects. Here, we demonstrate that the antidepre...

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Detalles Bibliográficos
Autores principales: Chowdhury, Golam M. I., Zhang, Jie, Thomas, Monique, Banasr, Mounira, Ma, Xiaoxian, Pittman, Brian, Bristow, Linda, Schaeffer, Eric, Duman, Ronald, Rothman, Douglas, Behar, Kevin, Sanacora, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345902/
https://www.ncbi.nlm.nih.gov/pubmed/27067013
http://dx.doi.org/10.1038/mp.2016.34