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Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects
Several drugs have recently been reported to induce rapid antidepressant effects in clinical trials and rodent models. Although the cellular mechanisms involved remain unclear, reports suggest that increased glutamate transmission contributes to these effects. Here, we demonstrate that the antidepre...
Autores principales: | Chowdhury, Golam M. I., Zhang, Jie, Thomas, Monique, Banasr, Mounira, Ma, Xiaoxian, Pittman, Brian, Bristow, Linda, Schaeffer, Eric, Duman, Ronald, Rothman, Douglas, Behar, Kevin, Sanacora, Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345902/ https://www.ncbi.nlm.nih.gov/pubmed/27067013 http://dx.doi.org/10.1038/mp.2016.34 |
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