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The Transient Receptor Potential Melastatin 7 Channel Regulates Pancreatic Cancer Cell Invasion through the Hsp90α/uPA/MMP2 pathway()

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a very poor prognosis. There is an urgent need to better understand the molecular mechanisms that regulate PDAC cell aggressiveness. The transient receptor potential melastatin 7 (TRPM7) is a nonselective cationic channel that...

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Detalles Bibliográficos
Autores principales: Rybarczyk, Pierre, Vanlaeys, Alison, Brassart, Bertrand, Dhennin-Duthille, Isabelle, Chatelain, Denis, Sevestre, Henri, Ouadid-Ahidouch, Halima, Gautier, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345960/
https://www.ncbi.nlm.nih.gov/pubmed/28284058
http://dx.doi.org/10.1016/j.neo.2017.01.004