Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

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Detalles Bibliográficos
Autores principales: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://www.ncbi.nlm.nih.gov/pubmed/28088401
http://dx.doi.org/10.1016/j.nbd.2017.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://www.ncbi.nlm.nih.gov/pubmed/28088401
http://dx.doi.org/10.1016/j.nbd.2017.01.003

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