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Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability
Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346071/ https://www.ncbi.nlm.nih.gov/pubmed/28088401 http://dx.doi.org/10.1016/j.nbd.2017.01.003 |