Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge

The unsaturated fatty acid, oleate exhibits anorexigenic properties reducing food intake and hepatic glucose output. However, its mechanism of action in the hypothalamus has not been fully determined. This study investigated the effects of oleate and glucose on GT1-7 mouse hypothalamic cells (a mode...

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Detalles Bibliográficos
Autores principales: Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346158/
https://www.ncbi.nlm.nih.gov/pubmed/28087336
http://dx.doi.org/10.1016/j.neuroscience.2016.12.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346158/
https://www.ncbi.nlm.nih.gov/pubmed/28087336
http://dx.doi.org/10.1016/j.neuroscience.2016.12.053

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