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Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge
The unsaturated fatty acid, oleate exhibits anorexigenic properties reducing food intake and hepatic glucose output. However, its mechanism of action in the hypothalamus has not been fully determined. This study investigated the effects of oleate and glucose on GT1-7 mouse hypothalamic cells (a mode...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346158/ https://www.ncbi.nlm.nih.gov/pubmed/28087336 http://dx.doi.org/10.1016/j.neuroscience.2016.12.053 |