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Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity
HIV-associated neurocognitive disorders (HAND) affect about 50% of infected patients despite combined antiretroviral therapy (cART). Ongoing compartmentalized inflammation mediated by microglia which are activated by HIV-infected monocytes has been postulated to contribute to neurotoxicity independe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346211/ https://www.ncbi.nlm.nih.gov/pubmed/28284222 http://dx.doi.org/10.1186/s12974-017-0829-2 |