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Support for phosphoinositol 3 kinase and mTOR inhibitors as treatment for lupus using in-silico drug-repurposing analysis

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with few treatment options. Current therapies are not fully effective and show highly variable responses. In this regard, large efforts have focused on developing more effective therapeutic strategies. Drug repurposing based on...

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Detalles Bibliográficos
Autores principales: Toro-Domínguez, Daniel, Carmona-Sáez, Pedro, Alarcón-Riquelme, Marta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346251/
https://www.ncbi.nlm.nih.gov/pubmed/28284231
http://dx.doi.org/10.1186/s13075-017-1263-7