Cargando…
Support for phosphoinositol 3 kinase and mTOR inhibitors as treatment for lupus using in-silico drug-repurposing analysis
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with few treatment options. Current therapies are not fully effective and show highly variable responses. In this regard, large efforts have focused on developing more effective therapeutic strategies. Drug repurposing based on...
Autores principales: | Toro-Domínguez, Daniel, Carmona-Sáez, Pedro, Alarcón-Riquelme, Marta E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346251/ https://www.ncbi.nlm.nih.gov/pubmed/28284231 http://dx.doi.org/10.1186/s13075-017-1263-7 |
Ejemplares similares
-
Shared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren’s syndrome uncovered through gene expression meta-analysis
por: Toro-Domínguez, Daniel, et al.
Publicado: (2014) -
Frailty Is Associated With Neutrophil Dysfunction Which Is Correctable With Phosphoinositol-3-Kinase Inhibitors
por: Wilson, Daisy, et al.
Publicado: (2020) -
Transcription Factor Activity Inference in Systemic Lupus Erythematosus
por: Lopez-Dominguez, Raul, et al.
Publicado: (2021) -
MetaGenyo: a web tool for meta-analysis of genetic association studies
por: Martorell-Marugan, Jordi, et al.
Publicado: (2017) -
Scoring personalized molecular portraits identify Systemic Lupus Erythematosus subtypes and predict individualized drug responses, symptomatology and disease progression
por: Toro-Domínguez, Daniel, et al.
Publicado: (2022)