Cargando…

Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue

BACKGROUND: Poor bone quality, increased fracture risks, and impaired bone healing are orthopedic comorbidities of type 1 diabetes (T1DM). Standard osteogenic growth factor treatments are inadequate in fully rescuing retarded healing of traumatic T1DM long bone injuries where both periosteal and bon...

Descripción completa

Detalles Bibliográficos
Autores principales: Filion, Tera M., Skelly, Jordan D., Huang, Henry, Greiner, Dale L., Ayers, David C., Song, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346267/
https://www.ncbi.nlm.nih.gov/pubmed/28283030
http://dx.doi.org/10.1186/s13287-017-0521-6