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Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue
BACKGROUND: Poor bone quality, increased fracture risks, and impaired bone healing are orthopedic comorbidities of type 1 diabetes (T1DM). Standard osteogenic growth factor treatments are inadequate in fully rescuing retarded healing of traumatic T1DM long bone injuries where both periosteal and bon...
Autores principales: | Filion, Tera M., Skelly, Jordan D., Huang, Henry, Greiner, Dale L., Ayers, David C., Song, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346267/ https://www.ncbi.nlm.nih.gov/pubmed/28283030 http://dx.doi.org/10.1186/s13287-017-0521-6 |
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