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GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway

GPR78 is an orphan G-protein coupled receptor (GPCR) that is predominantly expressed in human brain tissues. Currently, the function of GPR78 is unknown. This study revealed that GPR78 was expressed in lung cancer cells and functioned as a novel regulator of lung cancer cell migration and metastasis...

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Detalles Bibliográficos
Autores principales: Dong, Dan-Dan, Zhou, Hui, Li, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346323/
https://www.ncbi.nlm.nih.gov/pubmed/27697106
http://dx.doi.org/10.5483/BMBRep.2016.49.11.133