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GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway
GPR78 is an orphan G-protein coupled receptor (GPCR) that is predominantly expressed in human brain tissues. Currently, the function of GPR78 is unknown. This study revealed that GPR78 was expressed in lung cancer cells and functioned as a novel regulator of lung cancer cell migration and metastasis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346323/ https://www.ncbi.nlm.nih.gov/pubmed/27697106 http://dx.doi.org/10.5483/BMBRep.2016.49.11.133 |