Effects of FMO3 Polymorphisms on Pharmacokinetics of Sulindac in Chinese Healthy Male Volunteers

Sulindac is a nonsteroidal anti-inflammatory drug, which is clinically used for the ailments of various inflammations. This study investigated the allele frequencies of FMO3 E158K and E308G and evaluated the influences of these two genetic polymorphisms on the pharmacokinetics of sulindac and its me...

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Detalles Bibliográficos
Autores principales: Tang, Yong-Jun, Hu, Kai, Huang, Wei-Hua, Wang, Chong-Zhi, Liu, Zhi, Chen, Yao, Ouyang, Dong-Sheng, Tan, Zhi-Rong, Zhou, Hong-Hao, Yuan, Chun-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346382/
https://www.ncbi.nlm.nih.gov/pubmed/28331852
http://dx.doi.org/10.1155/2017/4189678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346382/
https://www.ncbi.nlm.nih.gov/pubmed/28331852
http://dx.doi.org/10.1155/2017/4189678

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