PPE38 Protein of Mycobacterium tuberculosis Inhibits Macrophage MHC Class I Expression and Dampens CD8(+) T Cell Responses

Suppression of CD8(+) T cell activation is a critical mechanism used by Mycobacterium tuberculosis (MTB) to escape protective host immune responses. PPE38 belongs to the unique PPE family of MTB and in our previous study, PPE38 protein was speculated to participate in manipulating macrophage MHC cla...

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Detalles Bibliográficos
Autores principales: Meng, Lu, Tong, Jingfeng, Wang, Hui, Tao, Chengwu, Wang, Qinglan, Niu, Chen, Zhang, Xiaoming, Gao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346565/
https://www.ncbi.nlm.nih.gov/pubmed/28348981
http://dx.doi.org/10.3389/fcimb.2017.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346565/
https://www.ncbi.nlm.nih.gov/pubmed/28348981
http://dx.doi.org/10.3389/fcimb.2017.00068

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