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PPE38 Protein of Mycobacterium tuberculosis Inhibits Macrophage MHC Class I Expression and Dampens CD8(+) T Cell Responses
Suppression of CD8(+) T cell activation is a critical mechanism used by Mycobacterium tuberculosis (MTB) to escape protective host immune responses. PPE38 belongs to the unique PPE family of MTB and in our previous study, PPE38 protein was speculated to participate in manipulating macrophage MHC cla...
Autores principales: | Meng, Lu, Tong, Jingfeng, Wang, Hui, Tao, Chengwu, Wang, Qinglan, Niu, Chen, Zhang, Xiaoming, Gao, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346565/ https://www.ncbi.nlm.nih.gov/pubmed/28348981 http://dx.doi.org/10.3389/fcimb.2017.00068 |
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