CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins

Hyperactive Ras signaling has strong oncogenic effects causing several different forms of cancer. Hyperactivity is frequently induced by mutations within Ras itself, which account for up to 30% of all human cancers. In addition, hyperactive Ras signaling can also be triggered independent of Ras by e...

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Detalles Bibliográficos
Autores principales: Riecken, Lars Björn, Zoch, Ansgar, Wiehl, Ulrike, Reichert, Sabine, Scholl, Ingmar, Cui, Yan, Ziemer, Mirjana, Anderegg, Ulf, Hagel, Christian, Morrison, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346635/
https://www.ncbi.nlm.nih.gov/pubmed/27793041
http://dx.doi.org/10.18632/oncotarget.12919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346635/
https://www.ncbi.nlm.nih.gov/pubmed/27793041
http://dx.doi.org/10.18632/oncotarget.12919

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