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CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins
Hyperactive Ras signaling has strong oncogenic effects causing several different forms of cancer. Hyperactivity is frequently induced by mutations within Ras itself, which account for up to 30% of all human cancers. In addition, hyperactive Ras signaling can also be triggered independent of Ras by e...
Autores principales: | Riecken, Lars Björn, Zoch, Ansgar, Wiehl, Ulrike, Reichert, Sabine, Scholl, Ingmar, Cui, Yan, Ziemer, Mirjana, Anderegg, Ulf, Hagel, Christian, Morrison, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346635/ https://www.ncbi.nlm.nih.gov/pubmed/27793041 http://dx.doi.org/10.18632/oncotarget.12919 |
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