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The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma

Metastatic cancer cells are characterized by their ability to degrade and invade through extracellular matrix. We previously showed that the Tks adaptor proteins, Tks4 and Tks5, are required for invadopodia formation and/or function in Src-transformed fibroblasts and a number of human cancer cell ty...

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Detalles Bibliográficos
Autores principales: Iizuka, Shinji, Abdullah, Christopher, Buschman, Matthew D., Diaz, Begoña, Courtneidge, Sara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346654/
https://www.ncbi.nlm.nih.gov/pubmed/27802184
http://dx.doi.org/10.18632/oncotarget.12954